Multi-Peptide Micro-Infusion System 2.0 GHK-Cu + PDRN + NAD⁺ For Hooded Eyelids

Core Regenerative Trio

• Copper Tripeptide-1 (GHK-Cu): Your anchor peptide for visible matrix renewal and wrinkle softening, especially effective when delivered via micro-infusion to support sagging lids.
• PDRN (Sodium DNA): A polynucleotide that supports the skin’s natural renewal process and post-stamp comfort in the delicate eyelid area.
• NAD+ (Nicotinamide Adenine Dinucleotide): A cellular cofactor that supports skin energy, repair, and renewal at the mitochondrial level. 

Lid-Firming & Matrix Peptides

• Eyeseryl® (Acetyl Tetrapeptide-5): A de-puffing and fluid-balance peptide that helps reduce the look of heaviness and morning swelling around the upper lid area.
• Palmitoyl Tripeptide-38: Signals multiple ECM constituents, including collagens I, III, and IV, for a smoother, firmer, more refined lid contour.
• Acetyl Tetrapeptide-2: A firmness and elasticity peptide that supports dermal architecture and bounce in laxity-prone eyelid skin. 

Texture, Elasticity & Structural Support

• Adenosine: A wrinkle-appearance softener that helps smooth crepey eyelid texture and fine lines.
• Sodium Heparin: A heparan-sulfate-inspired support active that helps improve barrier feel, resilience, and fine-line appearance.
• Caffeine: Micro-circulation support that helps tighten the appearance of loose eyelid skin and complements Eyeseryl® for a fresher-looking lid contour. 

Hydration & Comfort System

• Sodium Hyaluronate (High Molecular Weight): Forms a moisture-locking surface film for lasting hydration and immediate smoothing.
• Sodium Hyaluronate (Low Molecular Weight): Supports deeper hydration to soften the look of crepey texture.
• Glyceryl Glucoside: Supports natural moisture channels for enhanced hydration and skin resilience.
• Betaine: Balances and soothes the skin while helping maintain hydration under stress.
• Beta-Glucan: Supports visible remodeling and helps calm post-stamp micro-inflammation.
• Ectoin: An extremolyte-derived stress protector that helps shield delicate eyelid skin from dehydration and environmental stress. 

Vehicle & Delivery System

• Aqua (Water): Purified water base.
• Glycerin: A humectant that draws moisture to the skin for lasting hydration.
• Propanediol: A lightweight, skin-friendly solvent that supports active delivery.
• Pentylene Glycol: A hydrating solvent with mild antimicrobial-boosting properties.
• Polyquaternium-51: A skin-mimicking, breathable film former that helps actives stay in place while keeping skin comfortable. 

Preservative & Stability System

• Phenoxyethanol: A broad-spectrum preservative that helps keep the formula fresh and safe.
• Ethylhexylglycerin: A preservative booster and skin-conditioning support ingredient.
• Citric Acid: A pH adjuster used to support formula stability and skin compatibility. 

No added fragrance. No silicones. Drug-free. Designed for micro-infusion and consistent at-home use on the delicate upper eyelid area.

LummaSculpt® combines precision micro-infusion technology with a multi-active serum built around PDRN, NAD⁺, copper peptides, Eyeseryl®, and Palmitoyl Tripeptide-38.

The 0.25mm needles create temporary micro-channels that allow the serum to bypass the stratum corneum (the barrier that blocks over 95 percent of traditional topicals) and reach the dermal layer where sagging, crepey texture, and lost firmness actually originate.

This improves absorption by up to 30x compared to surface application, supports collagen renewal and elastic fiber restoration, and creates a healthier, more lifted eyelid environment—all in a professional-grade, at-home routine.

Most users notice early improvements within 2–4 weeks of consistent use. The first changes are typically reduced crepey texture, smoother eyelid skin, and a more lifted, open-eye appearance.

More significant firming, wrinkle softening, and visible reduction in hooding typically build over 6–12 weeks, depending on your starting point and consistency. Skin renewal is gradual—progress photos every 4 weeks help you see changes your eyes get used to daily.

Most users describe the sensation as a mild tingling or light pressure—more like a firm facial massage than a "needle" feeling. Our 0.25mm precision needles are designed to stimulate the dermal layer without drawing blood or causing significant discomfort.

You may notice slight pinkness or warmth for 30–60 minutes after treatment—this is completely normal and indicates the micro-channels are active. If you have sensitive skin, start with lighter pressure and fewer stamps, then build up as your skin adjusts.

We recommend twice per week, with at least 2–3 rest days between sessions to allow your skin to complete its natural renewal cycle.

• Week 1: Start with one session to test comfort and skin response.
• Week 2+: Move to twice weekly (e.g., Monday and Thursday, or Tuesday and Saturday).

Consistency matters more than frequency. Twice weekly for 12 weeks will outperform sporadic daily use.

Our Upper-Eye system uses precision 0.25mm needles only. This depth reaches the upper dermis where collagen remodeling and circulation signals are most active—without causing bleeding, bruising, or irritation to the delicate periorbital area.

Unlike the NLF (nasolabial fold) system, we do not recommend progressing to deeper needles around the eyes. The 0.25mm depth is optimized for this sensitive zone and delivers excellent results safely.

Virtually none. You may experience mild pinkness or a slightly "flushed" appearance for 30–60 minutes post-treatment. This fades quickly and can be covered with mineral makeup if needed.

The micro-channels close within approximately 30–60 minutes. Most users perform their treatment in the evening and wake up with no visible evidence of the session—just brighter, more refreshed-looking eyes.

Stamp along the brow bone and upper orbital rim (the firm bony arc above your eye) in a line from inner corner to outer corner—stay 5–7mm above the lash line. For hooded lids and sagging skin, stamp along the brow bone and the firm area just above the crease.

Avoid the thin, mobile eyelid skin that moves when you blink and never stamp directly on the soft lid tissue. Only stamp on the brow bone and upper orbital rim where you feel firm support underneath.

Yes, but with timing considerations:

• Before fillers: You can use the Micro-Infusion System right up until your filler appointment. Some users find that pre-treating the area improves skin quality and filler integration.
• After fillers: Wait at least 2–4 weeks after injectable fillers before resuming micro-infusion in the treated area. This allows the filler to fully settle and reduces any risk of displacement.

If you're unsure, consult your injector. Many aesthetic practitioners now recommend micro-infusion between filler appointments to extend results and improve skin quality.

Yes. The Botanique Paris® Upper-Eye Micro-Infusion System is designed for all Fitzpatrick skin types (I–VI) and works across a range of under-eye concerns—from early fine lines to established dark circles and puffiness.

Our serum is fragrance-free, silicone-free, and formulated without harsh penetration enhancers that can trigger sensitivity. The postbiotic and barrier-support actives (Bifida Ferment Lysate, Allantoin, Beta-Glucan, Ectoin) are specifically included to keep the delicate eye area calm between sessions.

Note: Avoid use on broken, infected, or actively inflamed skin. If you have a history of keloid scarring or are currently using prescription retinoids, consult your dermatologist before starting.

Not at all. While the LummaSculpt® Upper-Eye Micro-Infusion Serum features over 25 actives and co-actives (excluding water; HALOXYL® counted as one complex), they're selected and balanced for perfect synergy—not overload.

Most actives are gentle peptides, hydrators, and skin-calming agents, formulated at clinically-researched concentrations with supportive ingredients that reinforce comfort, barrier strength, and tolerance. Plus, soothing co-actives like Ectoin, Beta-Glucan, Panthenol, Allantoin, and Bifida Ferment Lysate are included specifically to buffer and help prevent irritation.

For most users—even those with sensitivity—this means you benefit from deep, multi-layered renewal without risk of "doing too much." As always, start gradually and follow provided usage guidance, but this serum is formulated for consistent, visible results with minimal risk of irritation or overwhelm.

To ensure optimal results and protect your delicate under-eye area, please follow these post-application guidelines:

• Do not touch or rub the treated area. Gentle tapping is all that's needed—the skin around the eyes is fragile, and rubbing can cause irritation or disrupt micro-channels.
• Avoid applying other strong actives (such as retinol, exfoliating acids, or benzoyl peroxide) to the under-eye area for at least 48 hours. Combining too many powerful ingredients may lead to irritation.
• Wait at least 4 hours before applying makeup, sunscreen, or other products on the treated skin—ideally overnight. This gives skin time to reseal and absorb all actives.
• Do not use on broken, sunburned, or infected skin. Wait until the area is fully healed before resuming.
• Do not wash the area or get it wet for at least 4 hours. Water can dilute the formula and disrupt the actives' penetration.
• Steer clear of the lash line and eyelids. Keep product to the orbital bone to prevent accidental eye exposure.
• Avoid waxing, threading, or in-office treatments (like chemical peels or lasers) on the eye contour for at least 7 days after use.
• Minimize direct sun exposure immediately after application, and always use sunscreen the next morning—newly treated skin can be extra vulnerable.
• Do not use more than recommended. Overuse may not improve results and may increase risk of redness, stinging, or sensitivity.
• Discontinue if you notice persistent stinging, itching, swelling, or rash, and consult a healthcare provider if symptoms worsen.

Summary: Gentle handling, minimal product layering, sun protection, and patience with the healing process are key for the best, safest results. When in doubt, follow the included usage guide or reach out to our support team.

We strongly recommend using only the LummaSculpt® serum with our micro-infusion system.

Here's why: not all serums are formulated for transdermal delivery. Many contain fragrances, essential oils, preservatives, or pH levels that can cause irritation or adverse reactions when delivered past the skin barrier—especially in the sensitive eye area.

Our serum is specifically engineered for micro-infusion—with a pH-balanced, irritant-free formula and actives dosed for dermal delivery, not surface application.

Yes. We offer a 365-day money-back guarantee on all Micro-Infusion System purchases.

If you don't see the de-puffing and brightening results you hoped for after consistent use, simply contact us within 365 days for a full refund—no questions, no hassle. We only win when you see real results.

Three key differences:

1. Precision vs. drag: Derma-rollers drag across the skin at inconsistent angles, creating uneven micro-tears. Our stamping mechanism delivers perpendicular, controlled penetration at a consistent depth—less trauma, better channels. This matters even more in the delicate eye area.
2. Integrated delivery: Rollers are separate from your serum. You roll, then apply, and hope absorption happens. Our system combines the micro-infusion device with a purpose-built serum, ensuring actives enter the channels while they're open.
3. Targeted application: Rollers cover broad areas indiscriminately. Our precision head lets you target the under-eye crescent specifically—right where dark circles and puffiness live.

Think of it as the difference between a scattershot and a precision instrument.

Yes, with proper care. You can reuse a cartridge if you sanitize it after each session:

1. Rinse the head under warm water to remove serum residue.
2. Soak in 70 percent isopropyl alcohol for 10 minutes.
3. Air-dry with needles facing up.

For optimal performance, we recommend replacing the head after approximately 5–8 uses. Needles gradually dull with use, and sharper needles create cleaner channels with less drag—especially important for the delicate eye area.

Pro tip: Mark each cartridge with a small dot after each use to track your count. If you ever notice bent needles, increased discomfort, or visible wear, replace immediately.

Absolutely. The system is designed to be intuitive:

1. Twist off the needle head, add 0.5mL of serum with the dropper, secure back on.
2. Clean and dry the upper eyelid area.
3. Stamp gently along the brow bone and upper orbital rim (12–15 stamps per side), staying on the firm bone above your crease.
4. Pour any remaining serum onto fingertips and massage over the brow bone, upper eyelid (gently), and temple area.
5. Let absorb—no rinsing for 8–12 hours.

Each 0.5mL session is calibrated specifically for bilateral upper eyelid treatment—both eyes, from inner corner to outer corner, along the brow bone and upper orbital rim.

If you're treating additional areas (crow's feet extending toward temples, forehead lines, etc.), you may need additional serum. Our multi-bottle bundles are designed for users who want to address multiple facial zones.

The Upper Eyelid Micro-Infusion System is ideal for:

• Adults struggling with hooded, sagging, or drooping upper eyelids that make eyes look heavy and tired
• Those with crepey, wrinkled eyelid texture that creases makeup
• Anyone noticing loss of lid definition and visible aging around the eyes
• Those considering blepharoplasty who want to try a non-surgical option first
• Post-blepharoplasty users who want to maintain results and prevent future sagging
• Anyone who wants professional-grade delivery without surgical risk or scars
• People who've tried countless eye creams without meaningful results

Not recommended for: Those with active eye infections, eczema, or open wounds in the treatment area; those currently on Accutane; those with a history of keloid scarring (consult your dermatologist first).

After 3–4 months of consistent use, many users see meaningful firming, lifting, and improved skin quality that persists for some time after stopping.

However, skin biology is ongoing. If you completely stop any skincare routine, your eyelids will gradually return toward their baseline over months. Most users find that switching to a lighter maintenance schedule (once weekly, or a few times per month) helps preserve results without the full twice-weekly commitment.

Most eye creams fail for one reason: they never actually reach the dermis.

The stratum corneum (your skin's outer barrier) blocks over 95 percent of topically applied actives. You can have the best ingredients in the world, but if they're sitting on the surface, they're not reaching where collagen collapse and elastic fiber breakdown actually happen.

LummaSculpt® solves the delivery problem:

• 0.25mm micro-infusion creates temporary channels that guide actives directly to the dermal layer—bypassing the barrier that blocks ordinary eye creams.
• Multi-pathway formulation addresses sagging (Eyeseryl® + GHK-Cu), crepey texture (Adenosine + Carnosine), wrinkles, and barrier health simultaneously—not just one mechanism.
• Clinically-dosed actives at levels that match published research, not trace amounts for label decoration.

It's not magic. It's better delivery plus smarter formulation—built for people who are done hoping their next eye cream will finally work.

Most brands sell you a device and a generic serum separately—you become the formulator, hoping they work together.

LummaSculpt® was engineered as a complete system:

• Delivery + formula, built together. The 0.25mm precision head is designed specifically for our serum's viscosity and active profile.
• 13 hero actives, not 1 token ingredient. PDRN, NAD⁺, GHK-Cu, Eyeseryl®, Palmitoyl Tripeptide-38, Adenosine, Carnosine, and more—each targeting a different pathway in upper eyelid aging.
• Recovery built in. Bifida Ferment Lysate, Allantoin, Ectoin, and Beta-Glucan keep the delicate eyelid area comfortable enough to maintain a consistent twice-weekly routine.

One system. One serum. One job: deliver what your upper eyelids actually need, where they actually need it.